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Impact of Polyphenols on Inflammatory and Oxidative Stress Factors in Diabetes Mellitus: Nutritional Antioxidants and Their Application in Improving Antidiabetic Therapy

FIGURE 5 ROS, mitochondrial depolarization (JC-1) and apoptosis results in DRG neurons Excessive and persistent increases in intracellular calcium concentrations–an important secondary messenger in all physiological events–is an important cause of mitochondrial oxidative stress that leads to cell death

Ingredients_Antioxidants

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This is supported by the study showing enhanced strength and muscular endurance in the leg muscles trained under systemically induced anaerobic conditions by normobaric hypoxic exposure (Manimmanakorn et al., 2013)